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C#CCC(c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)N(CCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccc(Cl)c1F

Reaction #402590

DOI: 10.1039/C8SC04228D

C#CC[C@H](c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)N(CCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccc(Cl)c1F

Reaction #1604532

3-chloro-N-[(R)-1-(7-chloro-4-oxo-3-phenylamino-3,4-dihydro-quinazolin-2-yl)-but-3-ynyl]-N-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)propyl]-2-fluoro-benzamide

Ausbeute 96.0%DOI: 10.6084/m9.figshare.5104873.v1

C#CC[C@H](c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)N(CCCN)C(=O)c1cccc(Cl)c1F

Reaction #1604533

N-(3-amino-propyl)-3-chloro-N-[(R)-1-(7-chloro-4-oxo-3-phenylamino-3,4-dihydro-quinazolin-2-yl)-but-3-ynyl]-2-fluoro-benzamide

Ausbeute 91.0%DOI: 10.6084/m9.figshare.5104873.v1

C#CCC(c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)N(CCCN)C(=O)c1cccc(Cl)c1F

Reaction #2429733

DOI: 10.1039/C8SC04228D