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CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3CO)ncc2c1
Reaction #225541
DOI: 10.1039/C8SC04228D
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3C=O)ncc2c1
Reaction #494789
101i
Ausbeute 52.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3CO)ncc2c1
Reaction #494790
101j
Ausbeute 76.2%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3C=O)ncc2c1
Reaction #755198
DOI: 10.1039/C8SC04228D
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Br)c3C=O)ncc2c1
Reaction #913946
DOI: 10.1039/C8SC04228D
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C#N)c5ccccc54)c3C=O)ncc2c1
Reaction #1112774
1-(3-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-2-formylphenyl)-1H-indole-3 carbonitrile
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccccc54)c3C=O)ncc2c1
Reaction #1112775
1-(3-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-2-formylphenyl)-1H-indole-3-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccccc54)c3CO)ncc2c1
Reaction #1112776
1-(3-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-2-(hydroxymethyl)phenyl)-1H-indole-3-carboxamide
Ausbeute 69.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1ccc2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccccc54)c3CO)ncc2c1
Reaction #1112778
desired product
Ausbeute 63.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5cccnc54)c3CO)ncc2c1
Reaction #1112779
desired product
Ausbeute 17.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5ccc(C(C)(C)O)cc5)n4)c3C=O)ncc2c1
Reaction #1112783
1-[3-(6-tert-butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-formyl-phenyl]-3-[4-(1-hydroxy-1-methyl-ethyl)-phenylamino]-1H-pyrazole-4-carboxylic acid amide
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5ccc(C(C)(C)O)cc5)n4)c3CO)ncc2c1
Reaction #1112784
1-[3-(6-tert-butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-hydroxymethyl-phenyl]-3-[4-(1-hydroxy-1-methyl-ethyl)-phenylamino]-1H-pyrazole-4-carboxylic acid amide
Ausbeute 91.2%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccc(-c6ccccc6F)nc54)c3CO)ncc2c1
Reaction #1112814
1-[3-(6-tert-Butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-hydroxymethyl-phenyl]-6-(2-fluoro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide
Ausbeute 91.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccc(-c6ccccc6Cl)nc54)c3CO)ncc2c1
Reaction #1112816
1-[3-(6-tert-Butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-hydroxymethyl-phenyl]-6-(2-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccc(Br)nc54)c3CO)ncc2c1
Reaction #1112818
6-bromo-1-[3-(6-tert-butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-hydroxymethyl-phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccc(C(O)CO)nc54)c3CO)ncc2c1
Reaction #1112820
1-[3-(6-tert-butyl-8-fluoro-1-oxo-1H-phthalazin-2-yl)-2-hydroxymethyl-phenyl]-6-(1,2-dihydroxy-ethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid amide
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3C=O)ncc2c1
Reaction #1272205
101i
Ausbeute 52.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3CO)ncc2c1
Reaction #1272206
101j
Ausbeute 76.2%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3C=O)ncc2c1
Reaction #2156896
title compound
Ausbeute 68.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(Cl)c3CO)ncc2c1
Reaction #2156897
title compound
Ausbeute 65.5%DOI: 10.6084/m9.figshare.5104873.v1
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