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2618

C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)/C=C/c2ccc(Cl)c(O)c2)C1=O
Reaction #7419
title compound
Ausbeute 83.8%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1(c2ccccc2)CCNC1
Reaction #10460
title compound
Ausbeute 99.9%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(C#N)c(N)c(NC(=O)C(C)(C)C)c(N2CC[C@H](N(C)C)C2)c1-c1ccccc1
Reaction #45833
compound
Ausbeute 43.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2[nH]c(C(C)(C)C)nc2c1C#N
Reaction #45834
2-tert-Butyl-7-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-5-methyl-6-phenyl-1H-benzimidazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
CC(c1cccc(OC(F)(F)F)c1)C1(O)CCCCC1N1CC[C@H](N)C1.Cl.Cl
Reaction #57102
2-[(3S)-3-aminopyrrolidin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethylcyclohexanol Dihydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
CN[C@H]1CCN(C2CCCCC2(O)C(C)c2cccc(C(F)(F)F)c2)C1.Cl.Cl
Reaction #57103
2-[(3S)-3-(methylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethylcyclohexanol Dihydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
CC(c1cccc(C(F)(F)F)c1)C1(O)CCCCC1N1CC[C@H](N(C)C)C1.Cl.Cl
Reaction #57104
2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethylcyclohexanol Dihydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
Cl.Cl.N[C@@H]1CCN(CC(c2ccc3ccccc3c2)C2(O)CCCCC2)C1
Reaction #57119
1-[2-[(3R)-3-aminopyrrolidin-1-yl]-1-(2-naphthyl)ethyl]cyclohexanol Dihydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
CN[C@@H]1CCN(CC(c2ccc3ccccc3c2)C2CCCCC2O)C1.Cl.Cl
Reaction #57120
2-[(3R)-3-(methylamino)pyrrolidin-1-yl-1-(2-naphthyl]ethyl}cyclohexanol Dihydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
CCCCOc1ccc2c(c1)CCN(c1ccc(N3CC[C@@H](N(C)CCS(C)(=O)=O)C3)c(F)c1)C2=O
Reaction #156592
6-Butoxy-2-(3-fluoro-4-{(R)-3-[(2-methanesulfonylethyl)methylamino]pyrrolidin-1-yl}phenyl)-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CCCCOc1ccc2c(c1)CCN(c1ccc(N3CC[C@@H](N(C)C(C)C)C3)c(F)c1)C2=O
Reaction #156593
6-Butoxy-2-{3-fluoro-4-[(R)-3-(isopropylmethylamino)pyrrolidin-1-yl]phenyl}-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(OS(=O)(=O)C(F)(F)F)ccc4C3=O)cc2F)C1
Reaction #156596
Trifluoromethanesulfonic acid 2-[4-((R)-3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl ester
DOI: 10.6084/m9.figshare.5104873.v1
COC1CCN(c2ccc3c(c2)CCN(c2ccc(N4CC[C@@H](N(C)C)C4)c(F)c2)C3=O)CC1
Reaction #156597
2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-6-(4-methoxypiperidin-1-yl)-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(N5CCCCC5)ccc4C3=O)cc2F)C1
Reaction #156598
2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-6-piperidin-1-yl-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(-c5ccc(F)cc5)ccc4C3=O)cc2F)C1
Reaction #156599
2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-6-(4-fluorophenyl)-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CCCCOc1ccc2c(c1)CCN(c1ccc(N3CCC(N4CCN(C(C)=O)CC4)C3)cc1)C2=O
Reaction #156600
2-{4-[3-(4-Acetylpiperazin-1-yl)pyrrolidin-1-yl]phenyl}-6-butoxy-3,4-dihydro-2H-isoquinolin-1-one
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(C(=O)O)ccc4C3=O)cc2F)C1
Reaction #156603
2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1ccc2c(c1)CCN(c1ccc(N3CC[C@@H](N(C)C)C3)c(F)c1)C2=O
Reaction #156604
2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid methyl ester
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NC1=N[C@@]2(c3cccc(Br)c3)CNC[C@H]2CS1)c1ccccc1
Reaction #164758
N-[(4aR,7aS)-7a-(3-Bromophenyl)-4a,5,6,7-tetrahydro-4H-pyrrolo[3,4-d][1,3]thiazin-2-yl]benzamide
DOI: 10.6084/m9.figshare.5104873.v1
Nc1cccc([C@]23CNC[C@H]2CSC(NC(=O)c2ccccc2)=N3)c1
Reaction #164761
title compound
Ausbeute 159.8%DOI: 10.6084/m9.figshare.5104873.v1
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