#2409

CNC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 46.0%750 AstraZeneca ELN dataset

CNC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 41.6%750 AstraZeneca ELN dataset

CCONC(=O)c1ccccc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Ausbeute 74.5%750 AstraZeneca ELN dataset

Cc1cc(Nc2cc(Nc3ccccc3C(=O)NOCCO)c(C(F)(F)F)cn2)n(C)n1

Ausbeute 48.6%750 AstraZeneca ELN dataset

CNC(=O)c1ccc(F)cc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Ausbeute 36.2%750 AstraZeneca ELN dataset

CONC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 0.0%750 AstraZeneca ELN dataset

CONC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 0.0%750 AstraZeneca ELN dataset

CONC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 71.6%750 AstraZeneca ELN dataset

CONC(=O)c1c(Nc2cc(Nc3cc(C)nn3C)ncc2C(F)(F)F)cccc1OC

Ausbeute 56.9%750 AstraZeneca ELN dataset

CONC(=O)c1ccc(F)cc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Reaction #203057

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)

CONC(=O)c1ccc(F)cc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Reaction #1133160

2-[[2-[(2,5-dimethylpyrazol-3-yl)amino]-5-(trifluoromethyl)-4-pyridyl]amino]-4-fluoro-N-methoxy-benzamide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_10

CNC(=O)c1ccc(F)cc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Reaction #1133161

2-[[2-[(2,5-dimethylpyrazol-3-yl)amino]-5-(trifluoromethyl)-4-pyridyl]amino]-4-fluoro-N-methyl-benzamide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_10

CNC(=O)c1ccc(F)cc1Nc1cc(Nc2cc(C)nn2C)ncc1C(F)(F)F

Reaction #2230748

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (4/10)