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228204

C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(COCCO)c(F)c2F)c(F)c1
Reaction #49003
2-(4-ethynyl-2-fluoro-phenylamino)-3,4-difluoro-N-(2-hydroxy-ethoxy)-5-(2-hydroxy-ethoxymethyl)-benzamide
Ausbeute 68.2%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CCC(=O)c2ccc(C#Cc3ccc(C(=O)O)c(F)c3)cc21
Reaction #52346
title compound
Ausbeute 27.1%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #52347
oil
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #52349
oil
Ausbeute 73.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)Cc1ccc(C#Cc2ccc3c(c2)C(C)(C)CN(C2CC2)C3)cc1F
Reaction #52358
title compound
Ausbeute 47.4%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CN(C2CC2)Cc2ccc(C#Cc3ccc(CC(=O)O)c(F)c3)cc21
Reaction #52359
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CCC(=O)c2ccc(C#Cc3ccc(C(=O)O)c(F)c3)cc21
Reaction #79913
title compound
Ausbeute 27.1%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #79916
solid
Ausbeute 41.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #79917
oil
Ausbeute 73.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CN(C2CC2)Cc2ccc(C#Cc3ccc(CC(=O)O)c(F)c3)cc21
Reaction #79928
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NCc1ccc(Cl)c(-n2nc(-c3ccc(C#Cc4cc(Cl)ccc4Cl)cc3F)[nH]c2=O)c1)C1CC1
Reaction #87770
desired product
Ausbeute 36.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(NCc1ccc(Cl)c(-c2nn(-c3ccc(C#CC4CC4)cc3F)c(=O)[nH]2)c1)C(F)(F)F
Reaction #87839
desired title product
Ausbeute 43.3%DOI: 10.6084/m9.figshare.5104873.v1
NCc1ccc(Cl)c(-c2nn(-c3ccc(C#CC4CC4)cc3F)c(=O)[nH]2)c1
Reaction #87840
desired product
Ausbeute 83.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)C(=O)NCc1ccc(Cl)c(-c2nn(-c3ccc(C#CC4CC4)cc3F)c(=O)[nH]2)c1
Reaction #87841
desired product
Ausbeute 32.2%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(C#C[Si](C)(C)C)cc4F)n(C)c(=O)c(C)c32)c1
Reaction #162845
N-{3-[3-cyclopropyl-5-(2-fluoro-4-trimethylsilanylethynylphenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
Ausbeute 93.0%DOI: 10.6084/m9.figshare.5104873.v1
C#Cc1ccc(Nc2c3c(=O)n(C4CC4)c(=O)n(-c4cccc(NC(C)=O)c4)c3c(C)c(=O)n2C)c(F)c1
Reaction #162846
N-{3-[3-cyclopropyl-5-(4-ethynyl-2-fluorophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
Ausbeute 93.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)Cc1cc(F)c(F)cc1F
Reaction #164028
2,4,5-trifluorophenylacetic acid
Ausbeute 25.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(C#CCN(C)C)cc3F)n2-c2ccc(F)cc2)ccc1Cl
Reaction #171022
3-(4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorophenyl)-N,N-dimethylprop-2-yn-1-amine
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(C#CC[N+](C)(C)C)cc3F)n2-c2ccc(F)cc2)ccc1Cl.Cc1ccc(S(=O)(=O)[O-])cc1
Reaction #171023
3-(4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorophenyl)-N,N,N-trimethylprop-2-yn-1-aminium 4-methylbenzenesulfonate
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(C#CCO)cc3F)n2-c2ccc(F)cc2)ccc1Cl
Reaction #171098
3-(4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorophenyl)prop-2-yn-1-ol
Ausbeute 94.9%DOI: 10.6084/m9.figshare.5104873.v1
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