4-Hydroxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

CN(C)CCOc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O

Reaction #49376

4-[2-(dimethylamino)ethoxy]-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 53.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)NCCCON1Cc2cccc(-c3cc4cc(CN5CCCCC5)ccc4n3C(=O)OC(C)(C)C)c2C1=O

Reaction #49377

(3-(tert-butoxycarbonylamino)propoxy]-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 88.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OCCCO[Si](C)(C)C(C)(C)C)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49378

4-[3-(tert-butyldimethylsilyloxy)propoxy]-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 53.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OCc3ccccc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49402

4-benzyloxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 73.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)OCCOc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O

Reaction #49403

4-(2-isopropoxyethoxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 59.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CN(C)CCCOc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O

Reaction #49404

4-[3-(dimethylamino)propoxy]-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 39.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CN1CCN(CCCOc2ccc(-c3cc4cc(CN5CCCCC5)ccc4n3C(=O)OC(C)(C)C)c3c2CNC3=O)CC1

Reaction #49405

4-[3-(4-methylpiperazin-1-yl)propoxy]-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 58.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(C)(=O)=O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49406

4-methanesulfonyloxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 61.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)Cc3ccccc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49407

4-(a-toluenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 37.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccccc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49408

4-benzenesulfonyloxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 86.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(N)(=O)=O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49409

4-sulfamoyloxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 54.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccc(Cl)cc3F)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49411

4-(2-fluoro-4-chlorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 27.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1ccc(S(=O)(=O)Oc2ccc(-c3cc4cc(CN5CCCCC5)ccc4n3C(=O)OC(C)(C)C)c3c2CNC3=O)cc1C

Reaction #49412

4-(3,4-dimethylbenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 36.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1ccc(S(=O)(=O)Oc2ccc(-c3cc4cc(CN5CCCCC5)ccc4n3C(=O)OC(C)(C)C)c3c2CNC3=O)cc1F

Reaction #49413

4-(3-fluoro-4-methylbenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 46.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3cccc(F)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49414

4-(3-fluorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 60.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1c(Cl)cccc1S(=O)(=O)Oc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O

Reaction #49415

4-(2-methyl-3-chlorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 50.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1ccc(S(=O)(=O)Oc2ccc(-c3cc4cc(CN5CCCCC5)ccc4n3C(=O)OC(C)(C)C)c3c2CNC3=O)cc1Cl

Reaction #49416

4-(4-methyl-3-chlorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 47.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccc(F)c(Cl)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49417

4-(3-chloro-4-fluorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 17.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

Cc1ccccc1S(=O)(=O)Oc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O

Reaction #49418

4-(2-methylbenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 69.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccc(Cl)c(Cl)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21

Reaction #49419

4-(3,4-dichlorobenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone

Ausbeute 28.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06

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