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21321

c1ccc(C(=Nc2ccc3nc(-c4ccccc4)ccc3c2)c2ccccc2)cc1
Reaction #221850
DOI: 10.1039/C8SC04228D
CN(C)c1cc(-c2cccc(F)c2)nc2ccc(Br)cc12
Reaction #228905
DOI: 10.1039/C8SC04228D
C=Cc1ccc2nc(-c3ccccc3)cc(OC3CC(C(=O)OC)N(C(=O)OC(C)(C)C)C3)c2c1
Reaction #232949
DOI: 10.1039/C8SC04228D
COC(=O)C1CC(Oc2cc(-c3ccccc3)nc3cc(OC)c(Br)cc23)CN1C(=O)OC(C)(C)C
Reaction #256308
DOI: 10.1039/C8SC04228D
C=Cc1cc2c(OC3CC(C(=O)OC)N(C(=O)OC(C)(C)C)C3)cc(-c3ccccc3)nc2cc1OC
Reaction #283962
DOI: 10.1039/C8SC04228D
Fc1ccc(-c2ccc3cc(Br)ccc3n2)cc1
Reaction #286239
DOI: 10.1039/C8SC04228D
Cc1c(-c2cccc(C(F)(F)F)c2)nc2ccc(Br)cc2c1C(=O)O
Reaction #332326
6-bromo-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Ausbeute 87.2%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2ccc(Br)cc12
Reaction #332327
methyl 6-bromo-3-(methyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
Ausbeute 152.6%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12
Reaction #332328
product
Ausbeute 64.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2nc(-c3cccc(C(F)(F)F)c3)c(C)c(C(=O)O)c2cc1Br
Reaction #332331
6-bromo-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Ausbeute 44.2%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(Br)cc12
Reaction #332332
methyl 6-bromo-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
Ausbeute 85.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(S(=O)(=O)C(C)C)cc12
Reaction #332333
methyl 3-methyl-6-[(1-methylethyl)sulfonyl]-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
Ausbeute 69.2%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2nc(-c3cccc(C(F)(F)F)c3)c(C)c(C(=O)O)c2cc1Br
Reaction #332382
6-bromo-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Ausbeute 78.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(Br)cc12
Reaction #332383
methyl 6-bromo-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
Ausbeute 68.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(S(=O)(=O)C(C)C)cc12
Reaction #332384
methyl 3-methyl-6-[(1-methylethyl)sulfonyl]-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
Ausbeute 90.1%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccc(C(F)(F)F)cc2)nc2ccc(Br)cc2c1C(=O)O
Reaction #332421
powder
Ausbeute 98.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1c(C)c(-c2ccc(C(F)(F)F)cc2)nc2ccc(Br)cc12
Reaction #332422
desired product
Ausbeute 98.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #332423
solid
Ausbeute 65.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(C(F)(F)F)c2)nc2ccc(Br)cc2c1C(=O)O
Reaction #332426
6-bromo-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Ausbeute 116.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc2c1C(=O)O
Reaction #332427
3-methyl-6-(methylsulfonyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Ausbeute 45.3%DOI: 10.6084/m9.figshare.5104873.v1
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