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O=C(O)c1cn(C2CC2F)c2c(Cl)c(N3CCN(CC(=O)N4CCOCC4)CC3)c(F)cc2c1=O
Reaction #209856
DOI: 10.1039/C8SC04228D
O=C(O)c1cn([C@H]2C[C@H]2F)c2c(Cl)c(N3CCN(CC(=O)N4CCOCC4)CC3)c(F)cc2c1=O
Reaction #339030
8-Chloro-6-fluoro-1-[(1S,2R)-2-fluorocyclopropyl]-7-[4-(2-morpholin-4-yl-2-oxoethyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cn([C@@H]2C[C@@H]2F)c2c(Cl)c(N3C[C@H](CNC4CC4)[C@H](F)C3)c(F)cc2c1=O
Reaction #511938
8-chloro-7-[(3S,4S)-3-cyclopropylaminomethyl-4-fluoro-1-pyrrolidinyl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Ausbeute 20.5%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cn(C2CC2F)c2c(Cl)c(N3CC(F)C(CNC4CC4)C3)c(F)cc2c1=O
Reaction #907561
DOI: 10.1039/C8SC04228D
O=C(O)c1cn([C@@H]2C[C@@H]2F)c2c(Cl)c(N3C[C@H](CNC4CC4)[C@H](F)C3)c(F)cc2c1=O
Reaction #2196004
8-chloro-7-[(3S,4S)-3-cyclopropylaminomethyl-4-fluoro-1-pyrrolidinyl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Ausbeute 20.5%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CCC[C@H]2CN(c3c(F)cc4c(=O)c(C(=O)O)cn([C@@H]5C[C@@H]5F)c4c3Cl)C[C@H]21
Reaction #2343266
titled compound
Ausbeute 55.9%DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cn([C@@H]2C[C@@H]2F)c2c(Cl)c(N3CC4=C(CNC4)C3)c(F)cc2c1=O
Reaction #2343271
titled compound
Ausbeute 10.7%DOI: 10.6084/m9.figshare.5104873.v1