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137801

CCOC(=O)c1cc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OC)C2)nc(C)n1
Reaction #72048
title compound
Ausbeute 21.4%DOI: 10.6084/m9.figshare.5104873.v1
CO[C@@H]1CN(c2cc(C)ncn2)CC[C@@H]1NC(=O)OCc1ccccc1
Reaction #72054
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1cc(N2CC[C@H](NC(=O)OCc3ccccc3)[C@H](OC)C2)ncn1
Reaction #72055
title compound
Ausbeute 25.7%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1cc(N2CC[C@H](N)[C@H](OC)C2)ncn1
Reaction #72056
title compound
Ausbeute 71.8%DOI: 10.6084/m9.figshare.5104873.v1
CCc1[nH]c(C(=O)N[C@H]2CCN(c3cc(C(=O)OC)ncn3)C[C@H]2OC)nc1Cl
Reaction #72057
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1cc(N2CCC(N3CCc4ccccc4NC3=O)CC2)ncn1
Reaction #161684
ethyl 6-[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-pyrimidine-4-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cc(N2CCC(N3CCc4ccccc4NC3=O)CC2)ncn1
Reaction #161685
6-[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-pyrimidine-4-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1cc(N2CCC(N3CCc4cc(OC)ccc4NC3=O)CC2)ncn1
Reaction #161686
ethyl 6-[4-(7-methoxy-2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-pyrimidine-4-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1
Reaction #161687
ethyl 6-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-pyrimidine-4-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
O=C(O)c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1
Reaction #161688
6-[4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-pyrimidine-4-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1)N1CCc2c1cccc2[N+](=O)[O-]
Reaction #161711
1-{1-[6-(4-nitro-2,3-dihydroindole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1cc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)ncn1)N1CCc2cc([N+](=O)[O-])ccc21
Reaction #161712
1-{1-[6-(5-nitro-2,3-dihydro-indole-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)N4CCc5ncc(Br)cc5C4)ncn3)CC1)C(=O)N2
Reaction #161713
3-{1-[6-(3-bromo-7,8-dihydro-5H-1,6-naphthyridin-6-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-7-methoxy-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3ncnc(C(=O)OC(C)(C)C)c3C)CC1)C(=O)N2
Reaction #161735
tert. butyl 6-[4-(7-methoxy-2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-5-methyl-pyrimidine-4-carboxylate
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3ncnc(C(=O)O)c3C)CC1)C(=O)N2
Reaction #161736
6-[4-(7-methoxy-2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-5-methyl-pyrimidine-4-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)n4ccc5nc(OCc6ccccc6)ccc54)ncn3)CC1)C(=O)N2
Reaction #161795
3-{1-[6-(5-benzyloxy-pyrrolo[3,2-b]pyridine-1-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-7-methoxy-1,3,4,5-tetrahydro-benzo[d][1,3]diazepin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)N(Cc4ccccc4)CC(F)(F)F)ncn3)CC1)C(=O)N2
Reaction #161806
6-[4-(7-methoxy-2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidin-1-yl]-pyrimidine-4-carboxylic acid benzyl-(2,2,2-trifluorethyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)N4Cc5cn[nH]c5C(C)(C)C4)ncn3)CC1)C(=O)N2
Reaction #161807
3-{1-[6-(7,7-dimethyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-7-methoxy-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CN(C(=O)c2cc(N3CCC(n4c(=O)[nH]c5ncccc54)CC3)ncn2)Cc2cn[nH]c21
Reaction #161808
1-{1-[6-(7,7-dimethyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3-dihydroimidazo[4,5-b]pyridin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)N4CCc5[nH]nc(-c6ccccc6)c5C4)ncn3)CC1)C(=O)N2
Reaction #161809
7-methoxy-3-{1-[6-(3-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
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