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135136

O=C1O[C@]2(CCN(C(=O)C3(c4ccc(OCc5ccncc5)cc4)CC3)C2)c2ccccc21
Reaction #591476
desired product
Ausbeute 89.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccccn5)cc4F)CC3)C2)c2ccccc21
Reaction #591478
desired product
DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(-c2ccc(C3(C(=O)N4CC[C@@]5(C4)OC(=O)c4ccccc45)CC3)cc2)cs1
Reaction #591493
(1R)-1′-({1-[4-(2-Amino-1,3-thiazol-4-yl)phenyl]cyclopropyl}carbonyl)-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccncc4)CCC3)C2)c2ccccc21
Reaction #591498
(1R)-1′-[(1-Pyridin-4-ylcyclobutyl)carbonyl]-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccccc21
Reaction #591517
(1R)-1′-{[1-(4-Bromophenyl)cyclopropyl]carbonyl}-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(OCc5ccncc5)cc4)CC3)C2)c2ccccc21
Reaction #645013
desired product
Ausbeute 89.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccccn5)cc4F)CC3)C2)c2ccccc21
Reaction #645016
desired product
DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(-c2ccc(C3(C(=O)N4CC[C@@]5(C4)OC(=O)c4ccccc45)CC3)cc2)cs1
Reaction #645031
(1R)-1′-({1-[4-(2-Amino-1,3-thiazol-4-yl)phenyl]cyclopropyl}carbonyl)-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccncc4)CCC3)C2)c2ccccc21
Reaction #645036
(1R)-1′-[(1-Pyridin-4-ylcyclobutyl)carbonyl]-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccccc21
Reaction #645055
product
Ausbeute 90.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(OCc5ccncc5)cc4)CC3)C2)c2ccccc21
Reaction #1056275
desired product
Ausbeute 89.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccccn5)cc4F)CC3)C2)c2ccccc21
Reaction #1056278
desired product
DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(-c2ccc(C3(C(=O)N4CC[C@@]5(C4)OC(=O)c4ccccc45)CC3)cc2)cs1
Reaction #1056293
(1R)-1′-({1-[4-(2-Amino-1,3-thiazol-4-yl)phenyl]cyclopropyl}carbonyl)-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccncc4)CCC3)C2)c2ccccc21
Reaction #1056298
(1R)-1′-[(1-Pyridin-4-ylcyclobutyl)carbonyl]-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccccc21
Reaction #1056318
product
Ausbeute 90.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccccn5)cc4F)CC3)C2)c2ccccc21
Reaction #2362734
desired product
DOI: 10.6084/m9.figshare.5104873.v1
Nc1nc(-c2ccc(C3(C(=O)N4CC[C@@]5(C4)OC(=O)c4ccccc45)CC3)cc2)cs1
Reaction #2362749
(1R)-1′-({1-[4-(2-Amino-1,3-thiazol-4-yl)phenyl]cyclopropyl}carbonyl)-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccncc4)CCC3)C2)c2ccccc21
Reaction #2362753
(1R)-1′-[(1-Pyridin-4-ylcyclobutyl)carbonyl]-3H-spiro[2-benzofuran-1,3′-pyrrolidin]-3-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccccc21
Reaction #2362773
product
Ausbeute 90.0%DOI: 10.6084/m9.figshare.5104873.v1