Teilstruktursuche

1302245

Cl.O=Cc1ccc(-c2cc3c(Nc4ccc(OCc5ccccc5)cc4)ncnc3cc2F)o1
Reaction #6932
solid
Ausbeute 61.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #6937
hydrochloride salt
DOI: 10.6084/m9.figshare.5104873.v1
CCCS(=O)(=O)CCNCC1(c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)CC=CO1
Reaction #6939
(4-(3-Fluorobenzyloxy)-3-chlorophenyl)-(6-(2-((2-propanesulphonyl-ethylamino)-methyl)-furan-2-yl)-quinazolin-4-yl)-amine
DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #6940
hydrochloride salt
DOI: 10.6084/m9.figshare.5104873.v1
O=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(C(F)(F)F)c4)c3c2)o1
Reaction #79398
5-(4-(4-Benzyloxy-3-trifluoromethylphenylamino)-quinazolin-6-yl)-furan-2-carbaldehyde
Ausbeute 84.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)cc4)c3c2)o1
Reaction #79423
N-{4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1-c1ccc(CNCCS(C)(=O)=O)o1
Reaction #79424
product
Ausbeute 48.1%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(C(F)(F)F)c5)cc4)c3c2)o1
Reaction #79426
6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-N-(4-{[3-(trifiuoromethyl) benzyl]oxy}phenyl)-4-quinazolinamine
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(F)c4)c3c2)o1
Reaction #79427
N-{3-fluoro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1
Reaction #79428
N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2cc3c(Nc4ccc(OCc5ccccc5)cc4)ncnc3cc2F)o1
Reaction #79430
N-[4-(Benzyloxy)phenyl]-7-fluoro-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
Ausbeute 61.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1occc1-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)c(C(F)(F)F)c3)c2c1
Reaction #79431
solid
Ausbeute 43.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1
Reaction #197732
DOI: 10.1039/C8SC04228D
CS(=O)(=O)CCNCc1ccc(-c2cc3c(Nc4ccc(OCc5ccccc5)cc4)ncnc3cc2F)o1
Reaction #206725
DOI: 10.1039/C8SC04228D
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1
Reaction #211936
DOI: 10.1039/C8SC04228D
Cl
Reaction #247798
DOI: 10.1039/C8SC04228D
CC(CN(C)C)NCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1
Reaction #256251
DOI: 10.1039/C8SC04228D
c1ccc(COc2ccc(Nc3ncnc4ccc(-c5ccc(CNc6cccnc6)o5)cc34)cc2)cc1
Reaction #374774
DOI: 10.1039/C8SC04228D
COc1cc(Nc2ncnc3ccc(-c4ccc(CNCCS(C)(=O)=O)o4)cc23)ccc1OCc1cccc(F)c1
Reaction #379241
DOI: 10.1039/C8SC04228D
NC(=O)C1CCCN1Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1
Reaction #404894
DOI: 10.1039/C8SC04228D
Seite 1Weiter