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1265148

Cn1cc(-c2cccc(-n3ncc4cc(C(C)(C)C)ccc4c3=O)c2C=O)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O
Reaction #155646
title compound
Ausbeute 69.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)OCc1c(-c2cc(Nc3ccc(N4CCN(C)CC4)cn3)c(=O)n(C)c2)cccc1N1CCn2c(cc3c2CC(C)(C)C3)C1=O
Reaction #175548
DOI: 10.1039/C8SC04228D
Cc1c(-c2cc(Nc3ccc(C(=O)N4CCOCC4)cn3)c(=O)n(C)c2)cccc1-c1c[nH]c2cc(N(C)C)ccc2c1=O
Reaction #203513
DOI: 10.1039/C8SC04228D
Cc1ccc2nc(-c3nc(-c4ccc(=O)n(C)c4)cnc3N)[nH]c2c1
Reaction #213371
DOI: 10.1039/C8SC04228D
CC(C)(O)c1cnn2c(-c3ccc(=O)n(-c4ncccc4C#N)c3)cnc2n1
Reaction #250777
DOI: 10.1039/C8SC04228D
CC(c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CCC(CC(C)(C)C#N)(c2ccccc2)OC1=O
Reaction #275726
DOI: 10.1039/C8SC04228D
Cc1cc(-c2ccc(=O)n(C)c2)cc(C)c1Br
Reaction #324759
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)OCc1c(-c2cc(Nc3ccc(N4CCN(C)CC4)cn3)c(=O)n(C)c2)cc(F)cc1N1CCn2c(cc3c2C2CCC3C2)C1=O
Reaction #383572
DOI: 10.1039/C8SC04228D
CC(c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O
Reaction #402032
DOI: 10.1039/C8SC04228D
CC(C)(O)c1cnn2c(-c3ccc(=O)n(-c4ncccc4C#N)c3)cnc2n1
Reaction #434885
title compound
DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(B(O)O)ccc1=O
Reaction #473112
title compound
DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(-c2cccc(Br)n2)ccc1=O
Reaction #473113
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
Reaction #493808
title compounds
Ausbeute 18.7%DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CC[C@](CC(C)(C)NS(C)(=O)=O)(c2ccccc2)OC1=O
Reaction #493815
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CC[C@](CC(C)(C)C#N)(c2ccc(F)cc2)OC1=O
Reaction #493817
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CC[C@](CC(C)(C)C#N)(c2ccccc2)OC1=O
Reaction #493909
2,2-dimethyl-3-((R)-2-oxo-3-((S)-1-(4-(6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-6-yl)propanenitrile
Ausbeute 94.3%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2ccc(Nc3cc(-c4cccc(-n5ncc6cc(C(C)(C)C)cc(F)c6c5=O)c4CO)cn(C)c3=O)nc2)CC1
Reaction #494791
101
Ausbeute 47.5%DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(-c2cc(F)cc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O
Reaction #494794
102c
Ausbeute 60.0%DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O
Reaction #494797
103c
Ausbeute 80.6%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3C=O)cn(C)c2=O)nc1
Reaction #494799
104a
Ausbeute 49.1%DOI: 10.6084/m9.figshare.5104873.v1
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