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Cc1cc(C(=O)N2CCOCC2)[nH]c1C=C1C(=O)N(C)c2ncnc(Nc3ccc(F)c(Cl)c3)c21
Reaction #182430
DOI: 10.1039/C8SC04228D
CCN(CC)CCN1CCc2[nH]c(C=C3C(=O)Nc4ncnc(Nc5ccc(F)c(Cl)c5)c43)c(C(F)(F)F)c2C1=O
Reaction #192125
DOI: 10.1039/C8SC04228D
O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)NCCN2CCOCC2)[nH]1
Reaction #221857
DOI: 10.1039/C8SC04228D
Cc1cc(C(=O)O)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21
Reaction #223529
DOI: 10.1039/C8SC04228D
Cc1cc(C(=O)N2CC(C)NC(C)C2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21
Reaction #235602
DOI: 10.1039/C8SC04228D
Cc1cc(C)c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]1
Reaction #249381
DOI: 10.1039/C8SC04228D
Cc1cc(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]c1C(=O)N1CCN(C)CC1
Reaction #262004
DOI: 10.1039/C8SC04228D
O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)N2CCOCC2)s1
Reaction #283664
DOI: 10.1039/C8SC04228D
Cc1c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]c2c1C(=O)N(CCN1CCOCC1)CC2
Reaction #382780
DOI: 10.1039/C8SC04228D
Cc1c(C(=O)N2CCN(C)CC2)c[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21
Reaction #397729
DOI: 10.1039/C8SC04228D
Cl
Reaction #406367
DOI: 10.1039/C8SC04228D
Cc1cc(C(=O)NCCN2CCOCC2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21.Cl
Reaction #484565
5-[4-(3-chloro-4-fluoro-phenylamino)-6-oxo-6,7-dihydro-pyrrolo[2,3-d]pyrimidin-5-ylidenemethyl]-4-methyl-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide hydrochloride
Ausbeute 39.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1[nH]c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)c(C)c1CCCN1CCOCC1.Cl
Reaction #484567
title compound
Ausbeute 10.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1=CC(C)C(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)=N1
Reaction #484570
title compound
Ausbeute 57.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)NCCN2CCOCC2)[nH]1
Reaction #484576
title compound
Ausbeute 16.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1[nH]c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)c(C)c1CCC(=O)O
Reaction #484581
title compound
Ausbeute 51.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1C(=O)Cc2c(Nc3ccc(F)c(Cl)c3)ncnc21
Reaction #484584
4-(3-chloro-4-fluoro-phenylamino)-7-methyl-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one
Ausbeute 98.1%DOI: 10.6084/m9.figshare.5104873.v1
Cc1[nH]c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)c(C)c1CCC(=O)N1CCCC1
Reaction #484585
title compound
Ausbeute 51.1%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(CCC(=O)N2CCN(C)CC2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21
Reaction #484587
title compound
Ausbeute 68.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1cc(CCC(=O)O)c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]1
Reaction #484588
title compound
Ausbeute 71.0%DOI: 10.6084/m9.figshare.5104873.v1
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