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1216580

Cc1nc(Cl)c(Cl)n1CCCCN1CC=C(c2ccccc2)CC1.Cl

Reaction #2888

4,5-dichloro-2-methyl-1-[4-(4-phenyl-1,2,3,6-tetrahydro-1-pyridyl)-butyl]-1H-imidazole hydrochloride

Ausbeute 189.2%DOI: 10.6084/m9.figshare.5104873.v1

$COc1cc(/C=C2\CC[C@H]3CCC[C@@H](c4ccc(Cl)cc4)N3C2=O)ccc1-n1cnc(C)c1$

Reaction #44647

title compound

DOI: 10.6084/m9.figshare.5104873.v1

CSC1=NC(c2cccc(Cl)c2)C(C(=O)NCC=Cc2ccccc2)=C(C)N1

Reaction #52902

title compound

DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(Oc1ccc(CCNC(=O)C=Cc2ccc(Cl)cc2)cc1)C(=O)O

Reaction #55071

2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionic acid

DOI: 10.6084/m9.figshare.5104873.v1

Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1

Reaction #71564

N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide

DOI: 10.6084/m9.figshare.5104873.v1

CCCCCCCCCCNC(=O)C=Cc1cccc(N2CC(C(=O)O)CC2=O)c1

Reaction #95073

title compound

DOI: 10.6084/m9.figshare.5104873.v1

COc1nc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)ccc1Br

Reaction #157737

title compound

DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(OC)c(=O)[nH]2)c(OC)c1$

Reaction #157822

6-{(E)-1-(4-tert-butylphenyl)-2-[(2R)-1-(2,4-dimethoxybenzyl)-5-oxopyrrolidin-2-yl]ethenyl}-3-methoxypyridin-2(1H)-one

Ausbeute 39.7%DOI: 10.6084/m9.figshare.5104873.v1

COc1ccc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)[nH]c1=O

Reaction #157823

title compound

Ausbeute 62.9%DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(N)c(OC)n2)c(OC)c1$

Reaction #157828

(5R)-5-[(E)-2-(5-amino-6-methoxypyridin-2-yl)-2-(4-tert-butylphenyl)ethenyl]-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one

DOI: 10.6084/m9.figshare.5104873.v1

COc1nc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)ccc1N

Reaction #157829

(5R)-5-[(E)-2-(5-amino-6-methoxypyridin-2-yl)-2-(4-tert-butylphenyl)ethenyl]pyrrolidin-2-one

Ausbeute 44.0%DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(C(C)OC(=S)SC)c(OC)n2)c(OC)c1$

Reaction #157836

O-[1-(6-{(E)-1-(4-tert-butylphenyl)-2-[(2R)-1-(2,4-dimethoxybenzyl)-5-oxopyrrolidin-2-yl]ethenyl}-2-methoxypyridin-3-yl)ethyl] S-methyl carbonodithioate

DOI: 10.6084/m9.figshare.5104873.v1

CCc1ccc(/C(=C/[C@H]2CCC(=O)N2Cc2ccc(OC)cc2OC)c2ccc(C(C)(C)C)cc2)nc1OC

Reaction #157837

(5R)-5-[(E)-2-(4-tert-butylphenyl)-2-(5-ethyl-6-methoxypyridin-2-yl)ethenyl]-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one

Ausbeute 71.6%DOI: 10.6084/m9.figshare.5104873.v1

CCc1ccc(/C(=C/[C@H]2CCC(=O)N2Cc2ccc(OC)cc2OC)c2ccc(C(C)(C)C)cc2)[nH]c1=O

Reaction #157838

6-{(E)-1-(4-tert-butylphenyl)-2-[(2R)-1-(2,4-dimethoxybenzyl)-5-oxopyrrolidin-2-yl]ethenyl}-3-ethylpyridin-2(1H)-one

Ausbeute 85.3%DOI: 10.6084/m9.figshare.5104873.v1

CCc1ccc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)[nH]c1=O

Reaction #157839

title compound

Ausbeute 57.6%DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(/C=C/CCO[Si](C)(C)C(C)(C)C)c(OC)n2)c(OC)c1$

Reaction #157843

(5R)-5-[(E)-2-{5-[(1E)-4-{[tert-butyl(dimethyl)silyl]oxy}but-1-en-1-yl]-6-methoxypyridin-2-yl}-2-(4-tert-butylphenyl)ethenyl]-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one

Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(CCCCOS(C)(=O)=O)c(OC)n2)c(OC)c1$

Reaction #157846

4-(6-{(E)-1-(4-tert-butylphenyl)-2-[(2R)-1-(2,4-dimethoxybenzyl)-5-oxopyrrolidin-2-yl]ethenyl}-2-methoxypyridin-3-yl)butyl methanesulfonate

DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(CCCCN(C)C)c(OC)n2)c(OC)c1$

Reaction #157847

(5R)-5-[(E)-2-(4-tert-butylphenyl)-2-{5-[4-(dimethylamino)butyl]-6-methoxypyridin-2-yl}ethenyl]-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one

DOI: 10.6084/m9.figshare.5104873.v1

$COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(C#N)c(OC)n2)c(OC)c1$

Reaction #157854

6-{(E)-1-(4-tert-butylphenyl)-2-[(2R)-1-(2,4-dimethoxybenzyl)-5-oxopyrrolidin-2-yl]ethenyl}-2-methoxypyridine-3-carbonitrile

Ausbeute 40.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1ccc(CN2C(=O)CCC2C=C(c2ccc(C(C)(C)C)cc2)c2ccc(C3(O)CCC3)c(OC)n2)c(OC)c1

Reaction #157856

5-{2-(4-tert-butylphenyl)-2-[5-(1-hydroxycyclobutyl)-6-methoxypyridin-2-yl]ethenyl}-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one

DOI: 10.6084/m9.figshare.5104873.v1

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