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1209626

COc1ccc(C(NC2=NC(C)(c3cc(NC(=O)c4ncc(C#N)cc4Cl)ccc3F)COC2)(c2ccccc2)c2ccc(OC)cc2)cc1
Reaction #294619
DOI: 10.1039/C8SC04228D
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OC[C@@H]1F
Reaction #492900
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OC[C@H]1F
Reaction #492933
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1=N[C@@](C)(c2nc(N)ccc2F)CO[C@@]1(C)C(F)(F)F
Reaction #561280
title compound
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1cnc(C(N)=O)c(Cl)c1
Reaction #561314
3-Chloro-5-cyano-pyridine-2-carboxylic acid amide
DOI: 10.6084/m9.figshare.5104873.v1
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OC[C@@H]1F
Reaction #604216
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OC[C@H]1F
Reaction #604251
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1=N[C@@](C)(c2nc(N)ccc2F)CO[C@@]1(C)C(F)(F)F
Reaction #625542
title compound
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)c1ncc(C#N)cc1Cl
Reaction #714867
tert-butyl 3-chloro-5-cyanopicolinate
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1cnc(C(=O)O)c(Cl)c1
Reaction #714868
3-chloro-5-cyanopicolinic acid
Ausbeute 93.2%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OCC1(F)F
Reaction #888144
DOI: 10.1039/C8SC04228D
CC1(C)OC(N)=NC(C)(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)C1(F)F
Reaction #905921
DOI: 10.1039/C8SC04228D
N#Cc1cnc(C(=O)Nc2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(N)=N3)c2)c(Cl)c1
Reaction #1017477
title compound
Ausbeute 48.5%DOI: 10.6084/m9.figshare.5104873.v1
C[C@@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)cnc2F)C[C@@H](C(F)(F)F)OC(N)=N1
Reaction #1017485
title compound
Ausbeute 22.2%DOI: 10.6084/m9.figshare.5104873.v1
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)COCC1(F)F.O=CO
Reaction #1273378
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(C(NC2=N[C@](C)(c3cc(NC(=O)c4ncc(C#N)cc4Cl)ccc3F)COC2)(c2ccccc2)c2ccc(OC)cc2)cc1
Reaction #2016698
title compound
Ausbeute 44.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)OC(N)=N[C@](C)(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)C1(F)F
Reaction #2028987
3-chloro-5-cyano-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4,6,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1
C[C@]1(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C(N)OCC1(F)F
Reaction #2029005
title compound
DOI: 10.6084/m9.figshare.5104873.v1