Teilstruktursuche

1197782

N#Cc1ccccc1N1CCN(C(=O)C2CC(NCc3ccc(F)cc3F)CN2Cc2cccc(F)c2F)CC1
Reaction #300787
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CC(N(Cc2ccc(F)cc2F)C(=O)OCC(Cl)(Cl)Cl)CC1C(=O)N1CCN(c2ccccc2C#N)CC1
Reaction #577806
title product
Ausbeute 97.0%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccccc1N1CCN(C(=O)C2CC(N(Cc3ccc(F)cc3F)C(=O)OCC(Cl)(Cl)Cl)CN2)CC1
Reaction #577807
crude product
Ausbeute 90.6%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccccc1N1CCN(C(=O)C2CC(N(Cc3ccc(F)cc3F)C(=O)OCC(Cl)(Cl)Cl)CN2Cc2cccc(F)c2F)CC1
Reaction #577808
{1-(2,3-Difluoro-benzyl)-5-[4-(2-cyano-phenyl)-piperazine-1-carbonyl]-pyrrolidin-3-yl}-(2,4-difluoro-benzyl)-carbamic acid 2,2,2-trichloro-ethyl ester
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccccc1N1CCN(C(=O)C2CC(NCc3ccc(F)cc3F)CN2Cc2cccc(F)c2F)CC1
Reaction #577809
final product
Ausbeute 8.0%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccccc1N1CCN(C(=O)C2CC(N(Cc3ccc(F)cc3F)C(=O)OCC(Cl)(Cl)Cl)CN2Cc2cccc(F)c2F)CC1
Reaction #778667
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N1CC(N(Cc2ccc(F)cc2F)C(=O)OCC(Cl)(Cl)Cl)CC1C(=O)N1CCN(c2ccccc2C#N)CC1
Reaction #913743
DOI: 10.1039/C8SC04228D
N#Cc1ccccc1N1CCN(C(=O)C2CC(N(Cc3ccc(F)cc3F)C(=O)OCC(Cl)(Cl)Cl)CN2)CC1
Reaction #922487
DOI: 10.1039/C8SC04228D