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1178853

CCOC(=O)c1cc(F)c(N2CC[C@H](NC(=O)OC(C)(C)C)C2)c(F)c1NC1CC1
Reaction #10384
title compound
Ausbeute 83.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(NCc3ccccc3)c3c(=O)n(NC(=O)OC(C)(C)C)c(=O)n(C4CC4)c3c2F)C1
Reaction #10404
{7-[(S)-3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-5-benzylamino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-2,4-dioxo-2H-quinazolin-3-yl}carbamic acid tert-butyl ester
Ausbeute 86.8%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(N)c3c(=O)n(NC(=O)OC(C)(C)C)c(=O)n(C4CC4)c3c2F)C1
Reaction #10406
{5-amino-7-[(S)-3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-1-cyclopropyl-6,8-difluoro-1,4-dihydro-2,4-dioxo-2H-quinazolin-3-yl}-carbamic acid tert-butyl ester
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(F)ccc1-c1nc(NCCN)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #58360
title compound
Ausbeute 89.6%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccccc1-c1nc(NCCNC(=N)NC#N)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #58366
title compound
Ausbeute 59.0%DOI: 10.6084/m9.figshare.5104873.v1
CCNc1nc(-c2ccc(F)cc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1
Reaction #173612
DOI: 10.1039/C8SC04228D
CS(=O)(=O)Nc1c(F)cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2CCc2ccccc2)cc1F
Reaction #175533
DOI: 10.1039/C8SC04228D
Cc1cc(F)ccc1-c1nc(NC2CCN(C)CC2)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #177676
DOI: 10.1039/C8SC04228D
Cl
Reaction #181047
DOI: 10.1039/C8SC04228D
CCCCc1nc(C(F)(F)F)ccc1C=CC(=O)NCc1cc(F)c(NS(C)(=O)=O)c(F)c1
Reaction #189866
DOI: 10.1039/C8SC04228D
Cc1cc(F)ccc1-c1nc(NCC(F)(F)F)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #193524
DOI: 10.1039/C8SC04228D
CCN(CC)CCCNc1nc(-c2cc(C(=O)NCC(=O)NC)ccc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1
Reaction #194565
DOI: 10.1039/C8SC04228D
Cc1cc(F)ccc1-c1nc(NC(C)(CO)CO)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #210919
DOI: 10.1039/C8SC04228D
Oc1cc(F)c(-n2cc(C(F)(F)F)cn2)c(F)c1
Reaction #221887
DOI: 10.1039/C8SC04228D
CSc1nc(Cl)c(CN)c(Nc2c(F)cccc2F)n1
Reaction #223724
DOI: 10.1039/C8SC04228D
CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc(NCC(O)C(O)CN)nc21
Reaction #231973
DOI: 10.1039/C8SC04228D
Cc1ccc(C(=O)NCc2ccccc2)cc1-c1nc(NCc2ncc[nH]2)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #235679
DOI: 10.1039/C8SC04228D
CS(=O)(=O)Nc1c(F)c(F)c(CN)c(F)c1F
Reaction #236360
DOI: 10.1039/C8SC04228D
Cc1cc(O)c(Cl)c(=O)n1-c1c(F)cccc1F
Reaction #238691
DOI: 10.1039/C8SC04228D
Cc1cc(F)ccc1-c1nc(NCC(F)(F)F)nc2c1ccc(=O)n2-c1c(F)cccc1F
Reaction #238811
DOI: 10.1039/C8SC04228D
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