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1016325

Cl
Reaction #204145
DOI: 10.1039/C8SC04228D
Cc1ccc2c(N3CCC(NC(=O)OC4CCOC4)C3)nc(-c3c(O)cccc3F)nc2c1
Reaction #231718
DOI: 10.1039/C8SC04228D
COCCOC(=O)NC1CCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1
Reaction #896560
DOI: 10.1039/C8SC04228D
Cl
Reaction #1232826
DOI: 10.1039/C8SC04228D
COCCOC(=O)N[C@@H]1CCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1
Reaction #1780183
(R)-2-methoxyethyl 1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate
Ausbeute 50.0%DOI: 10.6084/m9.figshare.5104873.v1
COCCOC(=O)N[C@@H]1CCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1.Cl
Reaction #1780184
(R)-2-methoxyethyl 1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3c(O)cccc3F)nc2c1
Reaction #2149521
(S)-tetrahydrofuran-3-yl(R)-1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate
Ausbeute 88.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3c(O)cccc3F)nc2c1.Cl
Reaction #2149522
(S)-tetrahydrofuran-3-yl(R)-1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate hydrochloride
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3c(O)cccc3F)nc2c1
Reaction #2166605
(S)-tetrahydrofuran-3-yl (R)-1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate
Ausbeute 88.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3c(O)cccc3F)nc2c1.Cl
Reaction #2166606
(S)-tetrahydrofuran-3-yl (R)-1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate hydrochloride
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
COCCOC(=O)N[C@@H]1CCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1
Reaction #2493342
pyrrolidin-3-ylcarbamate
Ausbeute 50.0%DOI: 10.6084/m9.figshare.5104873.v1
COCCOC(=O)N[C@@H]1CCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1.Cl
Reaction #2493343
(R)-2-methoxyethyl 1-(2-(2-fluoro-6-hydroxyphenyl)-7-methylquinazolin-4-yl)pyrrolidin-3-ylcarbamate hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1