تفاعل #992700

معادلة التفاعل

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

title product

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

→

title compound

2-amino-3-methyl-N-(1-methylethyl)benzeneacetamide

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىwas placed under a balloon of nitrogen overnight
2. 2
   ترشيحThen the reaction mixture was filtered through Celite® diatomaceous filter aid
3. 3
   أخرىThe solvent was removed with a rotary evaporator

الإجراء التجريبي

To 3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide (i.e. the title product of Step A) (0.40 g, 1.7 mmol) and 10% palladium on carbon (0.13 g) was added 20 mL of ethanol. The reaction mixture was placed under a balloon of nitrogen overnight. Then the reaction mixture was filtered through Celite® diatomaceous filter aid. The solvent was removed with a rotary evaporator to afford the title compound as a tan solid (0.29 g).

المصدر