تفاعل #992693

ord-2ba0fedd47514f2ea231865f164fe779

معادلة التفاعل

O=C(O)CC(O)C(=O)O
DL-Malic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
O=C=O
carbon dioxide
→
NNC(N)=[NH2+].NNC(N)=[NH2+].O=C([O-])CC(O)C(=O)[O-]
Bis(aminoguanidinium) DL-Malate

المتفاعلات

O=C(O)CC(O)C(=O)O
DL-Malic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
O=C=O
carbon dioxide

الكواشف

لا شيء

المذيبات

O
water

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe water was removed in vacuo
  2. 2
    درجة الحرارةwith heating to approximately 90° C. for 4 hours
  3. 3
    أخرىThe product was isolated as a white solid

الإجراء التجريبي

DL-Malic acid (2.0 g, 14.92 mmol) was dissolved in 5 ml of distilled water. Aminoguanidine bicarbonate (4.06 g, 29.83 mmol) was added in portions at room temperature (carbon dioxide gas was evolved) and the reaction was stirred at room temperature for 18 hours. The water was removed in vacuo with heating to approximately 90° C. for 4 hours. The product was isolated as a white solid.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08012277B2uspto-grants-2011_09