تفاعل #985303

معادلة التفاعل

5-Morpholin-4-yl-pent-3-yn-2-one

2-hexyl-isothiourea hydrobromide

N,N-diisopropyl ethylamine

→

4-(2-Hexylsulfanyl-6-methyl-pyrimidin-4-ylmethyl)-morpholine

المذيبات

DMF

ظروف التفاعل

الإجراء التجريبي

5-Morpholin-4-yl-pent-3-yn-2-one (1 g, 6 mmol) and 2-hexyl-isothiourea hydrobromide (1.06 g, 7 mmol) were dissolved under nitrogen in DMF (10 mL), then N,N-diisopropyl ethylamine (4.1 mL, 24 mmol) was added and stirring at the room temperature continued for 18 hours.

المصدر