تفاعل #985300
ord-344e2ede1a55402092f36b2c52f6ed11
معادلة التفاعل
Octyl cyanide
hydroxylamine hydrochloride
triethylamine
→
solid
المردود 27.0%
N-Hydroxy-nonanamidine
المردود 27.0%
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةat reflux over night
- 2استخلاصExtraction
الإجراء التجريبي
Octyl cyanide (2 g, 14 mmol) and hydroxylamine hydrochloride (2.495 g, 36 mmol) were dissolved in EtOH (10 mL) and treated with triethylamine (5 mL, 36 mmol) at reflux over night. Extraction: AcOEt/water. Silica gel chromatography: heptane/AcOEt 1:2 afforded a white solid (0.65 g, 26%). MS: m/z=173 (M +H).