تفاعل #985286

معادلة التفاعل

diethylaluminium chloride

2-dimethylaminobenzyllithium

→

[2-(dimethylamino)benzyl]-diethylaluminium

المردود 62.0%

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   أخرىthe reaction
2. 2
   ترشيحFiltration
3. 3
   أخرىthrough a D4 frit and removal of the solvent
4. 4
   workup.DISTILLATIONby distillation

الإجراء التجريبي

7.17 g (7.5 ml; 59.5 mmol) of diethylaluminium chloride were added dropwise to a suspension, cooled to −30° C., of 8.40 g (59.5 mmol) of 2-dimethylaminobenzyllithium in 150 ml of toluene in an inert nitrogen atmosphere. After slow warming to room temperature, the mixture was stirred for 15 hours in order to complete the reaction. Filtration through a D4 frit and removal of the solvent by distillation gave 8:05 g of [2-(dimethylamino)benzyl]-diethylaluminium (36.7 mmol/62%) as a colourless liquid by slow fractional distillation from the residue.

المصدر