تفاعل #985285

معادلة التفاعل

dimethylaluminium chloride

[2-(dimethylamino)benzyl]lithium

→

[2-(dimethyl-amino)benzyl]dimethylaluminium

المردود 58.0%

المذيبات

hexane

ظروف التفاعل

المعالجة

1. 1
   أخرىthe reaction
2. 2
   ترشيحFiltration
3. 3
   أخرىthrough a D4 frit and removal of the solvent
4. 4
   workup.DISTILLATIONby distillation

الإجراء التجريبي

10.0 ml (107.8 mmol) of dimethylaluminium chloride were added dropwise to a suspension, cooled to −30° C., of 15.21 g (107.8 mmol) of [2-(dimethylamino)benzyl]lithium in 250 ml of hexane in an inert nitrogen atmosphere. After slow warming to room temperature, the mixture was stirred for 14 hours in order to complete the reaction. Filtration through a D4 frit and removal of the solvent by distillation gave 11.95 g of [2-(dimethyl-amino)benzyl]dimethylaluminium (62.5 mmol/58%) as a colourless liquid by slow fractional distillation from the residue.

المصدر