تفاعل #981706

معادلة التفاعل

cyclopentylmethylbromide

sodium ethoxide

sodium

Imidazole

→

1-(cyclopentylmethyl)imidazole

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was heated
2. 2
   درجة الحرارةunder reflux
3. 3
   درجة الحرارةto reflux for a further 16 hours
4. 4
   workup.ADDITIONafter addition
5. 5
   workup.WAITThe mixture was then left
6. 6
   درجة الحرارةto cool

الإجراء التجريبي

A solution of sodium ethoxide was made by dissolving sodium (2.3 g, 0.1 mole) in absolute ethanol (100 ml). Imidazole (6.8 g, 0.1 mole) was then added. The mixture was heated under reflux and cyclopentylmethylbromide (16.3 g, 0.1 mole) was added dropwise. The reaction mixture was allowed to reflux for a further 16 hours after addition. The mixture was then left to cool.

المصدر