تفاعل #9815

معادلة التفاعل

6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

hydrogen

→

title compound

المردود 46.4%

6-Amino-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

المردود 46.4%

المذيبات

THF

MeOH

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe catalyst was filtered off
2. 2
   أخرىthe filtrate evaporated
3. 3
   أخرىthe residue chromatographed on silica

الإجراء التجريبي

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

المصدر