تفاعل #981374

معادلة التفاعل

6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid

thionyl chloride

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title product

2-Chlorocarbonyl-6,11-dihydro-11-oxodibenz[b,e]oxepin

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةHeat a solution of 5 gm
2. 2
   أخرىEvaporate the reaction mixture under vacuum to dryness
3. 3
   أخرىRepeat the evaporation with two 30 ml
4. 4
   أخرىCrystallize the residue from diisopropyl ether

الإجراء التجريبي

Heat a solution of 5 gm. of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid and 40 ml. of thionyl chloride under reflux for 20 minutes. Evaporate the reaction mixture under vacuum to dryness. Repeat the evaporation with two 30 ml. portions of carbon tetrachloride. Crystallize the residue from diisopropyl ether to obtain the title product.

المصدر