تفاعل #974946

معادلة التفاعل

(2-methyl-6,7-dihydrocyclopenta[e]indazol-8(2H)-ylidene)acetonitrile

ammonia ethanol

→

title compound

المردود 100.3%

2-(2-methyl-6,7-dihydrocyclopenta[e]indazol-8(2H)-ylidene)ethanamine

المردود 100.3%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe catalyst was filtered off through celite
2. 2
   تركيزthe filtrate was concentrated under reduced pressure

الإجراء التجريبي

To a solution of (2-methyl-6,7-dihydrocyclopenta[e]indazol-8(2H)-ylidene)acetonitrile (600 mg, 2.87 mmol) in ethanol (14 mL) were added Raney cobalt (6 g) and 2M ammonia/ethanol solution (14 mL), and the mixture was stirred under a hydrogen atmosphere at room temperature for 3 hr. The catalyst was filtered off through celite, and the filtrate was concentrated under reduced pressure to give the title compound (614 mg, yield 99%).

المصدر