تفاعل #95947

معادلة التفاعل

N-hydroxyethylethylenediamine

ethyl acetoacetate

lauric acid

→

4-lauroyloxyethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one

ظروف التفاعل

المعالجة

1. 1
   workup.DISTILLATIONAt 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off
2. 2
   أخرىwas effected at 200° to 210° C.
3. 3
   أخرىto distil off 18 g of water

الإجراء التجريبي

Into an apparatus similar to that in Example 1, were charged 104.2 g (1 mole) of N-hydroxyethylethylenediamine and 130.1 g (1 mole) of ethyl acetoacetate. At 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off. Then, after addition of 200.3 g (1 mole) of lauric acid, the esterification was effected at 200° to 210° C. to distil off 18 g of water and to obtain 4-lauroyloxyethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

المصدر