تفاعل #9555

معادلة التفاعل

1-(7-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol

1-(6-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol

→

1-(3-amino-7-benzylquinolin-4-ylamino)-2-methylpropan-2-ol

1-(3-amino-6-benzylquinolin-4-ylamino)-2-methylpropan-2-ol

ظروف التفاعل

الإجراء التجريبي

A modification of the method described in Part A of Examples 427–429 was used to reduce 1-(7-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol or 1-(6-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol. The reaction was shaken for one or two days to provide 1-(3-amino-7-benzylquinolin-4-ylamino)-2-methylpropan-2-ol or 1-(3-amino-6-benzylquinolin-4-ylamino)-2-methylpropan-2-ol.

المصدر