تفاعل #955447

معادلة التفاعل

sulphuric acid

nitric acid

2-chloro-6-fluorotoluene

→

2-chloro-6-fluoro-3-nitrotoluene

ظروف التفاعل

المعالجة

1. 1
   أخرىto attain room temperature
2. 2
   أخرى(20° C.)
3. 3
   workup.ADDITIONpoured
4. 4
   أخرىonto crushed ice

الإجراء التجريبي

To a vigorously stirred mixture of sulphuric acid (136 ml) and nitric acid (134 ml), maintained at 15° C. was added dropwise 2-chloro-6-fluorotoluene (100 g) over a period of 30 minutes. The mixture was alllowed to attain room temperature (20° C.), stirred for 70 minutes, then poured onto crushed ice. Solid 2-chloro-6-fluoro-3-nitrotoluene (70 g) was obtained after filtering and drying.

المصدر