تفاعل #95452

معادلة التفاعل

4-carbomethoxycyclohexane-1,1-diacetic acid anhydride

ammonia

→

9-Carbomethoxy-3-azaspiro[5.5]undecane-2,4-dione

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas slowly heated with
2. 2
   درجة الحرارةa free flame until the temperature
3. 3
   أخرىreached 200° C.
4. 4
   درجة الحرارةAfter cooling the product
5. 5
   أخرىwas used in the next step without purification

الإجراء التجريبي

A mixture of 4-carbomethoxycyclohexane-1,1-diacetic acid anhydride and concentrated aqueous ammonia solution was slowly heated with a free flame until the temperature reached 200° C. where it was kept for 1 hour. After cooling the product was used in the next step without purification.

المصدر