تفاعل #95434

معادلة التفاعل

hydantoin

4-nitrobenzaldehyde

ammonium acetate

acetic acid

→

5-(4'-nitrobenzylidene)-hydantoin

المردود 93.9%

المذيبات

n-butanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux temperature

الإجراء التجريبي

A mixture of 100 grams (1.0 mole) of hydantoin, 151 grams (1.0 mole) of 4-nitrobenzaldehyde, 77 grams (1.0 mole) of ammonium acetate, 120 grams (2.0 moles) of acetic acid, and 200 ml of n-butanol were held for 3 hours at reflux temperature. After the cooling, there were obtained 219 grams of 5-(4'-nitrobenzylidene)-hydantoin, corresponding to 94% of the theory based on hydantoin. The product had a melting point of 253°-254° C. and homogeneous by thin layer chromatography.

المصدر