تفاعل #95250

معادلة التفاعل

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   غسيلThe organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   تجفيفdried (MgSO4)
5. 5
   أخرىevaporated
6. 6
   أخرىto give 1.371 g

الإجراء التجريبي

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

المصدر