تفاعل #95043

معادلة التفاعل

4-cyanophenol

K2CO3

chloroacetonitrile

charcoal

→

4-cyanophenoxyacetonitrile

المذيبات

dimethylformamide

methylchloroform

water

ظروف التفاعل

المعالجة

1. 1
   أخرىThe compound of 4-cyanophenoxyacetonitrile was prepared
2. 2
   أخرىresulted in crystal formation
3. 3
   أخرىThe crystals were separated
4. 4
   ترشيحby filtering
5. 5
   غسيلwere then washed with water
6. 6
   أخرىAfter drying a pale tan solid
7. 7
   أخرىwas obtained which
8. 8
   درجة الحرارةat reflux temperature
9. 9
   ترشيحfiltered
10. 10
    ترشيحthe resulting crystals filtered
11. 11
    أخرىdried

الإجراء التجريبي

The compound of 4-cyanophenoxyacetonitrile was prepared by heating 29.8 g of 4-cyanophenol, 44.8 g of anhydrous K2CO3, 40 ml of dimethylformamide and 18.75 g of chloroacetonitrile with stirring in a round-bottomed three-necked flask at 70°-80° C. for 3 hours, after which time the reaction mixture was poured into an ice and water mixture, which resulted in crystal formation. The crystals were separated by filtering and were then washed with water. After drying a pale tan solid was obtained which was then dissolved in methylchloroform at reflux temperature, treated with activated charcoal and filtered. The filtrate was cooled to 5° C. and the resulting crystals filtered and dried to give the 4-cyanophenoxyacetonitrile.

المصدر