تفاعل #94898

معادلة التفاعل

1-methyldecylamine

3-phenyl-3-(4-nitrophenyl)propenoic acid

ethyl chloroformate

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title compound

المردود 51.0%

N-(1-Methyldecyl)-3-phenyl-3-(4-nitrophenyl)propenamide

المردود 51.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىsubstantially according to the procedure of Preparation 21
2. 2
   أخرىThe solid was recrystallized from hexane
3. 3
   أخرىgiving a small amount of material which
4. 4
   أخرىThe mother liquors were evaporated in vacuo
5. 5
   أخرىto give an oil which
6. 6
   ترشيحThe solid was filtered off

الإجراء التجريبي

The title compound was prepared from 3-phenyl-3-(4-nitrophenyl)propenoic acid via mixed anhydride formation using ethyl chloroformate, followed by reaction with 1-methyldecylamine, substantially according to the procedure of Preparation 21. The product was induced to solidify by trituration under hexane. The solid was recrystallized from hexane, giving a small amount of material which was discarded. The mother liquors were evaporated in vacuo to give an oil which solidified when stirred under acetonitrile. The solid was filtered off, giving a 51% yield of the title compound, m.p. 69°-71° C.

المصدر