تفاعل #94896

معادلة التفاعل

decylamine

3-phenyl-3-(4-nitrophenyl)propenoyl chloride

→

N-Decyl-3-phenyl-3-(4-nitrophenyl)propenamide

المذيبات

tetrahydrofuran

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   أخرىThe solvent was removed by evaporation in vacuo
2. 2
   أخرىthe residue was partitioned between ethyl acetate and water
3. 3
   أخرىThe layers were separated
4. 4
   غسيلthe ethyl acetate layer was washed with water
5. 5
   أخرىdried
6. 6
   أخرىevaporated in vacuo

الإجراء التجريبي

To a stirred solution of 5.89 g. of decylamine in 25 ml. of tetrahydrofuran was added a solution of 4.89 g. of 3-phenyl-3-(4-nitrophenyl)propenoyl chloride in 25 ml. of tetrahydrofuran, dropwise, during 20 minutes, at ice-bath temperature. The solvent was removed by evaporation in vacuo and the residue was partitioned between ethyl acetate and water. The layers were separated, and the ethyl acetate layer was washed with water, dried using sodium sulfate, and then evaporated in vacuo. This afforded 5.6 g. of the title compound, m.p. 91°-93° C.

المصدر