تفاعل #94632

معادلة التفاعل

3-Hydroxy-6-methyl-2-nitropyridine

→

2-amino-3-hydroxy-6-methylpyridine

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe catalyst was removed by filtration
2. 2
   تركيزthe filtrate was concentrated to dryness

الإجراء التجريبي

3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next step.

المصدر