تفاعل #94557

معادلة التفاعل

1-p-chlorophenyl-3-azabicyclo[3.1.0]hexane

sodium carbonate

1-adamantanecarboxylic acid chloride

→

3-(1-adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane

ظروف التفاعل

الإجراء التجريبي

A sample of 19.35 g of 1-p-chlorophenyl-3-azabicyclo[3.1.0]hexane, 10.59 g of sodium carbonate and 19.87 g of 1-adamantanecarboxylic acid chloride are reacted in accordance with Example 36, yielding the product 3-(1-adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane as a white solid, mp 163°-165° C.

المصدر