تفاعل #94476

معادلة التفاعل

4-Nitrostyrylsulfonyl chloride

4-nitrobenzamidine

triethylamine

→

N-(4-NITROSTYRYLSULFONYL)-4-NITROBENZAMIDINE

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   أخرىprepared
2. 2
   أخرىat 10° C
3. 3
   تركيزat 25° C., the mixture is concentrated under reduced pressure
4. 4
   workup.STIRRINGthe residual material stirred with water
5. 5
   أخرىcollected
6. 6
   أخرىTriturating the filter cake with acetone

الإجراء التجريبي

4-Nitrostyrylsulfonyl chloride (2.5 g., 0.01 mole) is added portion-wise to a solution of 4-nitrobenzamidine (1.65 g., 0.01 mole), prepared according to the procedure of L. Weintraub, et al., J. Org. Chem., 33, 1679 (1968), and triethylamine (1.01 g., 0.01 mole) in 50 ml. of acetone at 10° C. After stirring for a period of 1 hr. at 25° C., the mixture is concentrated under reduced pressure and the residual material stirred with water and collected. Triturating the filter cake with acetone provides N-(4-NITROSTYRYLSULFONYL)-4-NITROBENZAMIDINE, m.p. 173°-177° C.

المصدر