تفاعل #939051

معادلة التفاعل

methyl 3-nitroanthranilate

→

desired compound

Methyl 3-aminoanthranilate

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe 10% Pd/C was removed
2. 2
   workup.DISTILLATIONthe solvent was distilled off under reduced pressure

الإجراء التجريبي

To a solution of methyl 3-nitroanthranilate (1.44 g, 7.34 mmol) in methanol (50 mL) was added 10% Pd/C (300 mg), and the resulting mixture was stirred for 12 hours at room temperature under hydrogen atmosphere. The 10% Pd/C was removed, and the solvent was distilled off under reduced pressure, to give 1.22 (quantitative yield) of the desired compound in the form of a brown crystalline product.

المصدر