تفاعل #939019

معادلة التفاعل

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

المردود 35.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىto react at 240° C. for 5 minutes
2. 2
   استخلاصthe reaction solution was extracted with ether
3. 3
   غسيلwashed with dilute sulfuric acid
4. 4
   غسيلwashed with water
5. 5
   أخرىdried
6. 6
   أخرىevaporated
7. 7
   أخرىto remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   أخرىgiving

الإجراء التجريبي

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

المصدر