تفاعل #936117

معادلة التفاعل

thionyl chloride

pentadecanoic acid

thionyl chloride

pentadecanoic acid

→

pentadecanoyl chloride

المردود 63.9%

المذيبات

cyclohexane

ظروف التفاعل

المعالجة

1. 1
   أخرىthe flask was equipped with a 100 mL
2. 2
   درجة الحرارةunder heating
3. 3
   درجة الحرارةfurther the oil bath was maintained at 80° C. for one hour
4. 4
   أخرىFrom the resultant reaction mixture
5. 5
   أخرىwere removed the cyclohexane
6. 6
   أخرىThe resultant crude reaction product
7. 7
   workup.DISTILLATIONwas subjected to vacuum distillation

الإجراء التجريبي

In a one L (liter) two-necked flask were placed 160.0 g (0.66 mol) of pentadecanoic acid and 200 milliliter (mL) of cyclohexane, and the flask was equipped with a 100 mL dropping funnel containing 83.3 g (0.7 mol) of thionyl chloride and a reflux tube. Then, the pentadecanoic acid was completely dissolved under heating and stirring of the flask in an oil bath at 80° C. Thereafter the thionyl chloride was added dropwise over a period of 2 hours, and further the oil bath was maintained at 80° C. for one hour. From the resultant reaction mixture were removed the cyclohexane and the thionyl chloride under reduced pressure by means of an aspirator. The resultant crude reaction product was subjected to vacuum distillation. Thus 110.0 g (0.42 mol) of pentadecanoyl chloride was obtained in a yield of 63.9% based on the fed pentadecanoic acid.

المصدر