تفاعل #93370

ord-7270018c8e304ab09f9bfd27b2196627

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةwas refluxed for 1 hour
  2. 2
    درجة الحرارةAfter cooling, to the mixture
  3. 3
    استخلاصThe solution was extracted with chloroform
  4. 4
    غسيلThe extract was washed with water
  5. 5
    أخرىdried
  6. 6
    أخرىevaporated

الإجراء التجريبي

A mixture of 0.39 g of alpha-isopropyl-alpha-[2-[N-[3-(2-methoxyphenoxy)propyl]amino]ethyl]-3,4,5-trimethoxyphenylacetonitrile, 1 ml of 37% formalin, and 1 ml of 90% formic acid was refluxed for 1 hour. After cooling, to the mixture were added water and potassium carbonate to make it alkaline. The solution was extracted with chloroform. The extract was washed with water, dried, and evaporated to give 0.23 g of desired compound as a yellow oil.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04612329uspto-grants-1986_09