تفاعل #92933

معادلة التفاعل

1-bromo-2-(2-methylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

المردود 34.0%

المذيبات

diethyl ether

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction solvent was decanted
2. 2
   غسيلthe residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONThe residue was dissolved in hot acetonitrile
4. 4
   درجة الحرارةthe resulting solution was cooled
5. 5
   workup.ADDITIONdiluted with diethyl ether
6. 6
   أخرىThe solid was collected
7. 7
   أخرىrecrystallized twice from acetonitrile/diethyl ether

الإجراء التجريبي

A solution of 4.22 g (0.02 mol) of 1-bromo-2-(2-methylphenyl)-2-oxoethane, 2.64 g (0.032 mol) of 1-methylimidazole and 60 ml of diethyl ether was stirred at room temperature for approximately 17 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was dissolved in hot acetonitrile, and the resulting solution was cooled and diluted with diethyl ether. The solid was collected and recrystallized twice from acetonitrile/diethyl ether to afford 1.99 g of 1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as white needles. (34% yield) mp=152°-154° C.

المصدر