تفاعل #92932

معادلة التفاعل

1-bromo-2-(4-ethylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide

المردود 38.2%

المذيبات

diethyl ether

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction solvent was decanted
2. 2
   غسيلthe residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in a small amount of acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate
5. 5
   أخرىformed
6. 6
   أخرىThe solid was collected
7. 7
   أخرىrecrystallized from acetonitrile/ethyl acetate

الإجراء التجريبي

A solution of 4.41 g (0.019 mol) of 1-bromo-2-(4-ethylphenyl)-2-oxoethane and 1.65 g (0.02 mol) of 1-methylimidazole in 40 ml of diethyl ether was stirred at room temperature for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in a small amount of acetonitrile. The resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate formed. The solid was collected and recrystallized from acetonitrile/ethyl acetate to provide 2.26 g of 1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide as fine yellow brown needles. (38% yield) mp=177°-179° C.

المصدر