تفاعل #92813

معادلة التفاعل

Indolo[2,3-a]carbazole

3-bromo-p-terphenyl

potassium orthophosphate

→

N-(1,1′:4′,1″-terphenyl-3-yl)indolo[2,3-a]carbazole

المردود 67.5%

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةheated
2. 2
   درجة الحرارةto reflux for 16 h
3. 3
   أخرىAfter the completion of reaction
4. 4
   أخرىthe reaction was quenched with water
5. 5
   استخلاصThe reaction mixture was then extracted
6. 6
   تجفيفand the organic layer was dried over anhydrous sodium sulfate
7. 7
   أخرىevaporated to dryness under vacuum

الإجراء التجريبي

Indolo[2,3-a]carbazole (9.8 g) was dissolved in 150 ml of dry toluene under nitrogen. 12.9 g of 3-bromo-p-terphenyl, 0.65 g of tris(dibenzylideneacetone) dipalladium, 0.46 g of tri-t-butylphosphine and 40.3 g of potassium orthophosphate were added and heated to reflux for 16 h. After the completion of reaction, the reaction was quenched with water. The reaction mixture was then extracted using ethyl acetate; and the organic layer was dried over anhydrous sodium sulfate and evaporated to dryness under vacuum. Subsequent silica gel column chromatography using ethyl acetate/hexane (1:9) as eluent, yielded 12.6 g of N-(1,1′:4′,1″-terphenyl-3-yl)indolo[2,3-a]carbazole.

المصدر