تفاعل #9275

معادلة التفاعل

2-(1-butynyl)pyridine

O-mesitylenesulfonylhydroxyamine

Diethyl ether

→

N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

المردود 39.1%

المذيبات

dichloromethane

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwhile cooling on ice
2. 2
   أخرىto precipitate crystals, which
3. 3
   ترشيحwere collected by filtration
4. 4
   أخرىdried under reduced pressure

الإجراء التجريبي

After dissolving 2-(1-butynyl)pyridine (12.8 g) in dichloromethane (60 mL), a solution of O-mesitylenesulfonylhydroxyamine (Reference document: Synthesis, 1997, 1) (20 g) in dichloromethane (132 mL) was added dropwise while cooling on ice, and the mixture was stirred for 30 minutes. Diethyl ether (2 L) was added to the reaction mixture to precipitate crystals, which were collected by filtration and dried under reduced pressure to obtain N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (12.6 g) as colorless crystals.

المصدر