تفاعل #927259

معادلة التفاعل

hydrochloric acid

bromoform

2-pentyl-hept-1-ene

potassium t-butoxide

→

2,2-dibromo-1,1-dipentyl-cyclopropane

المردود 83.4%

المذيبات

water

—

pentanes

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONwas added slowly via addition funnel
2. 2
   أخرىThe resulting mixture was transferred to a separatory funnel
3. 3
   أخرىthe phases were separated
4. 4
   تجفيفThe organic layer was dried over MgSO4
5. 5
   ترشيحfiltered
6. 6
   أخرىThe solvent was removed from the filtrate in vacuo

الإجراء التجريبي

To a solution of 4.16 g (0.0247 mol) of 2-pentyl-hept-1-ene in 31 ml of pentanes, was added 4.95 g (0.0441 mol) of potassium t-butoxide. While cooling the resulting mixture to an internal temperature of 5° C., 4.01 ml ( 0.0459 mol) of bromoform was added slowly via addition funnel. The reaction mixture was allowed to warm naturally to room temperature and left overnight. To the reaction mixture was added 25 ml of water then 36 ml of 1 N hydrochloric acid. The resulting mixture was transferred to a separatory funnel and the phases were separated. The organic layer was dried over MgSO4 and filtered. The solvent was removed from the filtrate in vacuo to yield 7.00 g (83.4% of theory) of 2,2-dibromo-1,1-dipentyl-cyclopropane as an oil.

المصدر