تفاعل #927255

معادلة التفاعل

hexane

sodium hydroxide

hexanol

2,3-dibromopropene

→

2-bromo-3-hexyloxypropene

المردود 95.0%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىTo a three neck round bottom flask equipped with an addition funnel and an overhead stirrer
2. 2
   أخرىwere fed to the well-stirred reaction mixture over a 20 minute period
3. 3
   أخرىthe phases were separated
4. 4
   غسيلThe organic phase was washed with water and brine
5. 5
   تجفيفdried over magnesium sulfate
6. 6
   ترشيحfiltered
7. 7
   workup.DISTILLATIONThe product was fractionally distilled under reduced pressure

الإجراء التجريبي

To a three neck round bottom flask equipped with an addition funnel and an overhead stirrer was added 35 ml of hexane, 42 g of 50% sodium hydroxide and 0.50 g of tetra-n-butylammonium bromide. A mixture of 6.74 g of hexanol (66 mmol) and 20 g (100 mmol) of 2,3-dibromopropene were fed to the well-stirred reaction mixture over a 20 minute period. The reaction was stirred an additional 1 hour, then water was added, and the phases were separated. The organic phase was washed with water and brine, dried over magnesium sulfate, filtered and stripped. The product was fractionally distilled under reduced pressure to give 6.1 g of 95% pure 2-bromo-3-hexyloxypropene.

المصدر